| # | Club | P | W | D | L | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|
| 1 |  San Diego | 34 | 19 | 6 | 9 | +23 | 63 | |
| 2 |  Vancouver Whitecaps | 34 | 18 | 9 | 7 | +28 | 63 | |
| 3 |  Los Angeles FC | 34 | 17 | 9 | 8 | +25 | 60 | |
| 4 |  Minnesota United FC | 34 | 16 | 10 | 8 | +17 | 58 | |
| 5 |  Seattle Sounders | 34 | 15 | 10 | 9 | +10 | 55 | |
| 6 |  Austin | 34 | 13 | 8 | 13 | -8 | 47 | |
| 7 |  FC Dallas | 34 | 11 | 11 | 12 | -3 | 44 | |
| 8 |  Portland Timbers | 34 | 11 | 11 | 12 | -7 | 44 | |
| 9 |  Real Salt Lake | 34 | 12 | 5 | 17 | -11 | 41 | |
| 10 |  San Jose Earthquakes | 34 | 11 | 8 | 15 | -3 | 41 | |
| 11 |  Colorado Rapids | 34 | 11 | 8 | 15 | -12 | 41 | |
| 12 |  Houston Dynamo | 34 | 9 | 10 | 15 | -13 | 37 | |
| 13 |  St. Louis City | 34 | 8 | 8 | 18 | -14 | 32 | |
| 14 |  Los Angeles Galaxy | 34 | 7 | 9 | 18 | -20 | 30 | |
| 15 |  Sporting Kansas City | 34 | 7 | 7 | 20 | -24 | 28 |